This medicine is offered in four doses, varying in power from 3.75 to 15 milligrams of phentermine and 23 to 92 mg of topiramate.
Your doctor will decide whether phentermine is appropriate and safe for you.
May Be Helpful for Certain Eating Disorders
In a meta-analysis of six studies, individuals who took the ordinary dose of 27.5 mg of phentermine for 13 weeks lost an average of 13.9 pounds (6.3 kg) compared to 6.2 pounds (2.8 kg) in placebo groups (9Trusted Source).
Whilst ingesting a well-balanced, reduced-calorie diet and exercising regularly are the cornerstones of weight reduction, certain drugs can serve as powerful adjuncts.
A reduced-calorie dietIf you have excess weight to lose, eat 300–500 fewer calories every day. A registered dietitian can help you tailor this variety based on your own preferences and aims (4Trusted Source).
While phentermine has been proven to work for weight loss, it may work better when combined with topiramate (10Trusted Source).
However, you might construct a tolerance to the appetite-suppressing effects of phentermine in a few weeks. If that’s the scenario, your dose of this drug shouldn’t increase but quit using it.
Neurotransmitters are the body’s chemical messengers and include norepinephrine, serotonin, and dopamine.
In a different 12-week study, individuals with BED or bulimia nervosa were randomized to receive the drug combination or a placebo.
Whilst phentermine can be a useful short-term weight loss tool, you have to make healthy lifestyle modifications for long-term achievement.
Behavioral plans: Behavior changes comprises routine self-monitoring of food intake, physical activity, and your weight, also making adjustments as needed (4Trusted Source).
Bulimia nervosa involves exactly the same binge-eating behavior like BED, but includes behaviors, such as self-induced nausea, and in an attempt to compensate for the effects of binge eating (18Trusted Source).
Phentermine and topiramate — marketed under the brand name Qsymia — is a combination medicine used for weight loss (11Trusted Source, 21Trusted Source).
BED is characterized by eating large amounts of food, often quickly and into the point of discomfort. Additionally, it is connected with a feeling of losing control throughout the binge, as well as feelings of guilt or shame afterward (18Trusted Source).
While severe adverse effects are rare, research report several side effects of the phentermine and topiramate combination (15Trusted Source).
From the 1990s, phentermine was combined together with other weight loss medications. This drug combination was commonly referred to as fen-phen.
One such drug is phentermine — among the very popular weight loss drugs in the world.
Phentermine goes by the brand names Adipex-P, Lomaira, and Suprenza, or you can locate it in combination drugs for weight reduction, for example Qsymia.
Howeverthe FDA has approved phentermine together with topiramate for long-term use, since the dosage of the 2 ingredients is lower than the highest doses of these individual drugs (22Trusted origin ).